|
Symbol Name ID |
Apoe
apolipoprotein E MGI:88057 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Stroke |
Dysphagia |
Spasticity |
Spastic tetraparesis |
Fatigable weakness of bulbar muscles |
Fatigable weakness of swallowing muscles |
Fatigable weakness of respiratory muscles |
Motor neuron atrophy |
Amyotrophic lateral sclerosis |
Morphological central nervous system abnormality |
Cerebral cortical atrophy |
Neurofibrillary tangles |
Spinal cord compression |
Alzheimer disease |
Neurodegeneration |
Optic ataxia |
Abnormality of extrapyramidal motor function |
Parkinsonism |
Apraxia |
Fasciculations |
Myoclonus |
Paralysis |
Babinski sign |
Long-tract signs |
Dysarthria |
Language impairment |
Depression |
Emotional lability |
Disturbed sensory perception |
Anxiety |
Atypical behavior |
Personality changes |
Agitation |
Cognitive impairment |
Memory impairment |
Dementia |
Frontotemporal dementia |
Reduced consciousness |
Sleep abnormality |
Hyperreflexia |
Jaw hyperreflexia |
Lower limb hyperreflexia |
Dystonia |
Gait disturbance |
Gait imbalance |
Headache |
Seizure |
Paresthesia |
| Disease(s) Associated with APOE | ||||||||||||||||||||||||||||||||||||||||||||||||
| Alzheimer's disease 2 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Alzheimer's disease 3 | ||||||||||||||||||||||||||||||||||||||||||||||||
| amyotrophic lateral sclerosis | ||||||||||||||||||||||||||||||||||||||||||||||||
| cerebral infarction | ||||||||||||||||||||||||||||||||||||||||||||||||
| malaria | ||||||||||||||||||||||||||||||||||||||||||||||||
| multiple myeloma |
| Mouse Phenotypes | nervous system phenotype |
abnormal kindling response |
impaired blood-brain barrier function |
hypopituitarism |
cochlear inner hair cell degeneration |
cochlear outer hair cell degeneration |
decreased cerebral infarct size |
abnormal hippocampus morphology |
abnormal cerebral cortex morphology |
abnormal neuron morphology |
abnormal myelin sheath morphology |
abnormal dendrite morphology |
abnormal synapse morphology |
abnormal synaptic vesicle morphology |
cochlear ganglion degeneration |
abnormal sciatic nerve morphology |
abnormal astrocyte physiology |
|
| Availability | Mouse Genotype | |||||||||||||||||
| Apoetm1Bres/Apoetm1Bres | ||||||||||||||||||
| Apoetm1Unc/Apoetm1Unc | * | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/23/2024 MGI 6.23 |
|
|
|
||
Analysis Tools